Blackpool captain Charlie Adam is fit after a foot injury scare.
It was initially feared the Scotland midfielder might have broken a bone after getting hurt in last week's loss to Wigan but the problem has proved to be only bruising.
Adam's fellow midfielder David Vaughan is also hoping to feature after two games out with a hip injury.
Goalkeeper Matt Gilks is likely to continue after making his return from a broken kneecap against Wigan but defender David Carney (shoulder) is out for the season.
Newcastle skipper Kevin Nolan will return from suspension.
The midfielder has missed the last two games after reaching 10 bookings for the campaign, but could partner Cheick Tiote once again after the Ivory Coast international returned from a similar lay-off against Manchester United.
However, Tim Krul will deputise once again for keeper Steve Harper, who may need an minor operation on his knee, while midfielder Danny Guthrie will miss out with a shin problem.
French winger Hatem Ben Arfa is on target to be involved in the final three games of the campaign, but Leon Best (ankle), Dan Gosling (knee) and Alan Smith (ankle) remain on the sidelines.
Blackpool (from): Gilks, Eardley, Cathcart, Crainey, Evatt, Southern, Adam, Varney, Taylor-Fletcher, Campbell, Grandin, Baptiste, Sylvestre, Puncheon, Vaughan, Phillips, Ormerod, Beattie, Reid, Kornilenko, Rachubka, Kingson.
Newcastle (from): Krul, Sodeberg, Simpson, Ferguson, Enrique, Coloccini, Williamson, S. Taylor, R. Taylor, Perch, Tiote, Barton, Gutierrez, Nolan, Ireland, Vuckic, Tavernier, Richardson, Lovenkrands, Ameobi, Ranger, Kuqi.