Liverpool will make late checks will be made on the fitness of Jamie Carragher and Andy Carroll.
Carragher, captaining the side in the absence of Steven Gerrard, was knocked unconscious in a clash of heads with young full-back John Flanagan during Sunday's draw at Arsenal.
Carroll jarred a knee against the Gunners and was taken off as a precaution, but left-back Fabio Aurelio is unlikely to feature this weekend after sustaining a thigh problem at the Emirates Stadium.
Birmingham will be boosted by the return from injury of central defender Martin Jiranek.
The Czech Republic international has missed the last three games with a groin injury and abdominal complaint.
But he has returned to training and Blues manager Alex McLeish has confirmed he will be part of the squad to travel to Anfield.
Jiranek had formed an effective partnership with Roger Johnson after the loss of Scott Dann for the second half of the campaign with a hamstring injury.
Strikers Nikola Zigic (groin) and Obafemi Martins (leg) are again ruled out.
Liverpool (from): Reina, Flanagan, Skrtel, Carragher, Robinson, Lucas, Spearing, Kuyt, Meireles, Carroll, Suarez, Gulacsi, Kyrgiakos, Wilson, Shelvey, Poulsen, Rodriguez, Cole, Ngog.
Birmingham (from): Foster, Carr, Johnson, Jiranek, Ridgewell, Parnaby, Larsson, Gardner, Ferguson, Bowyer, Jerome, Phillips, Doyle, Hleb, Fahey, Derbyshire, Mutch, Davies, Bentley, Beausejour.