United boss Sir Alex Ferguson will check the fitness of Dimitar Berbatov before deciding whether to include the Bulgarian in his plans.
Berbatov missed Tuesday's goalless draw at Newcastle with a minor groin strain and with the Champions League semi-final first leg clash with Schalke looming, with Ferguson will not want to take any chances even though United are looking to avoid failing to score in three successive games for the first time since 2007.
Paul Scholes serves the second game of a three-match ban and Darren Fletcher (virus) is still out but full-back Rafael (hamstring) returns.
Key pair Mikel Arteta and Tim Cahill could return for the Toffees.
Arteta has missed four games with a hamstring injury while Cahill has been troubled by a foot problem for the past month.
Midfielder John Heitinga is doubtful after hobbling out of last week's win over Blackburn with a hamstring injury.
Jack Rodwell and Seamus Coleman are both pushing to start after substitute appearances last week but Louis Saha and Marouane Fellaini are long-term absentees.
United (from): Van der Sar, Kuszczak, Rafael, O'Shea, Brown, Ferdinand, Smalling, Vidic, Evans, Evra, Fabio, Valencia, Gibson, Anderson, Park, Carrick, Giggs, Nani, Rooney, Berbatov, Hernandez, Owen.
Everton (from): Howard, Hibbert, Jagielka, Distin, Baines, Coleman, Osman, Rodwell, Neville, Bilyaletdinov, Beckford, Arteta, Cahill, Gueye, Anichebe, Mustafi, Baxter, Vellios, Forshaw, McAleny, Nsiala, Mucha.