Maynor Figueroa returns for Wigan.
The Honduras defender has missed relegation-threatened Latics' last two games through suspension.
Veteran goalkeeper Mike Pollitt is unavailable after a minor elbow operation but Chris Kirkland will provide bench cover for first-choice Ali Al Habsi.
Roberto Martinez's men are otherwise at full strength for their penultimate home match of the season.
Mikel Arteta could come into contention for Everton.
The Spanish playmaker has missed the last five games with a hamstring injury but has been involved in training this week.
Midfielder Tim Cahill, who came off the bench at Manchester United last week, should be in the squad but is still unlikely to start due to a foot problem.
Utility man John Heitinga (hamstring) is doubtful while Louis Saha and Marouane Fellaini are out for the season with ankle injuries.
Wigan (from): Al Habsi, G Caldwell, Gohouri, Alcaraz, Watson, Figueroa, N'Zogbia, Diame, Moses, McCarthy, Rodallega, Stam, Lopez, Thomas, Gomez, McArthur, McManaman, Cleverley, S Caldwell, Sammon, Di Santo, Boyce, Thomas, Kirkland.
Everton (from): Howard, Hibbert, Distin, Jagielka, Baines, Coleman, Rodwell, Neville, Bilyaletdinov, Osman, Beckford, Cahill, Arteta, Gueye, Heitinga, Anichebe, Mustafi, Baxter, Duffy, Vellios, Forshaw, Mucha.