Carlisle could field an unchanged line-up for the sixth successive match in their final game.
Manager Greg Abbott has enjoyed an injury-free run-in and has no new problems or suspension worries as his side look to finish in the top half of the table.
Central defender Danny Livesey replaced Lubo Michalik during last week's 3-0 defeat at Dagenham & Redbridge and will be hoping to have impressed sufficiently to win a recall to the starting line-up, while strikers Paddy Madden and Rory Loy are also in contention.
On-loan Stoke winger Ben Marshall is sidelined with a season-ending ankle ligament injury, but will return to Brunton Park as a spectator to bid the fans farewell.
Abbott's Johnstone's Paint Trophy winners are already one point ahead of last season's tally of 58 and could squeeze into the top 10 with victory.
Yeovil manager Terry Skiverton will have captain Paul Huntington back.
Centre-back Huntington returns after sitting out the last two games due to the ban he received for his second sending off the season in the 2-2 draw with Bournemouth on April 23.
However, it remains to be seen if Huntington regains his place in the starting line-up with Skiverton hinting that he could stick with the same side that started the impressive 4-2 win over Colchester, the Glovers' biggest win of the season, last week.
That would mean Town again going for a 3-5-2 formation with Luke Ayling partnering Nathan Smith and Max Ehmer in a three-man backline.
Yeovil have no new injury problems but Andy Williams (ankle ligaments) remains missing as does fellow striker Sam Williams who has an unspecified injury.