Full-back O'Connor sustained the injury in the midweek win over Norwich but is hoping to start again, while manager Sean O'Driscoll has no new injury or suspension worries.
Rovers turned in arguably their best display of the season on Tuesday and O'Driscoll must decide whether to recall skipper Brian Stock to the starting line-up.
James Coppinger struck a hat-trick against Norwich and is expected to start alongside Billy Sharp up front while Martin Woods, Simon Gillett, Mark Wilson and John Oster will be hoping to continue in midfield.
O'Driscoll's side, still without Byron Webster (foot), James Chambers and Wayne Thomas (both knee) and James Hayter (hamstring), can move into second place with a third successive home win.
