Arsenal will have captain Cesc Fabregas (hamstring), Denilson (groin), Alex Song (calf) and Andrey Arshavin (virus)l back against the Magpies.
England teenager Jack Wilshere has now completed a three-match domestic ban, while fit-again Theo Walcott is pressing for a start having scored in the midweek Champions League defeat away to Shakhtar Donetsk.
Goalkeeper Manuel Almunia (elbow), centre-half Thomas Vermaelen (Achilles), midfielder Abou Diaby (ankle) and left-back Kieran Gibbs (knee) remain out, while long-term absentees Aaron Ramsey and Robin van Persie are close to a return.
Newcastle boss Chris Hughton will make a late decision on whether or not to include Sol Campbell in his squad.
The 36-year-old has trained all week after recovering from a thigh injury, but will have to wait until the last moment to discover if he will travel.
Steven Taylor is likely to be included after making the bench for last weekend's derby victory over Sunday following his return from a shoulder problem, while Leon Best (ankle) will resume training on Monday.
However, Steve Harper (shoulder), Hatem Ben Arfa (double leg fracture) and Dan Gosling (knee) remain on the sidelines.
Gunners (from): Fabianski, Clichy, Squillaci, Koscielny, Sagna, Nasri, Song, Wilshere, Fabregas, Walcott, Chamakh, Szczesny, Arshavin, Denilson, Bendtner, Vela, Djourou, Rosicky.
Toon (from): Krul, Soderberg, R. Taylor, Simpson, Perch, Ferguson, Enrique, Coloccini, Williamson, S. Taylor, Campbell, Kadar, Smith, Tiote, Barton, Routledge, Gutierrez, Guthrie, Vuckic, Tavernier, Donaldson, Nolan, Carroll, Ameobi, Lovenkrands, Ranger.