Colin Nish remains a doubt for the hosts. The striker suffered an ankle injury in scoring during the 4-2 loss at Aberdeen in Colin Calderwood's first match in charge and missed last Saturday's 1-0 loss at Dundee United.
David Wotherspoon should be fit to return after missing out at Tannadice, with Graham Stack (back), Darryl Duffy (metatarsal) and Merouane Zemmama (knee) still out.
Hearts winger Suso Santana is expected to be fit for the Edinburgh derby.
Santana missed two days of training following last Sunday's 3-0 loss at home to Kilmarnock but returned on Wednesday.
Jefferies has no other fresh concerns, with Andrew Driver (thigh), David Obua (groin) and Lee Wallace (knee) still absent.
Hibernian (from): Brown, Wotherspoon, Hogg, Bamba, De Graaf, Miller, Rankin, Nish, Riordan, Hanlon, Thicot, Stevenson, Galbraith, Dickoh, Grounds, McBride, Murray, Smith.
Hearts (from): Kello, Barr, Bouzid, Zaliukas, Stevenson, Palazuelos, Templeton, Elliot, Elliott, Santana, Balogh, Kyle, Jonsson, Mrowiec, J Thomson, C Thomson, Skacel, Novikovas.