The full-back missed the 2-0 defeat at Norwich on Saturday after suffering a thigh injury in training and the club have now revealed he will be out for around four to six weeks.
Striker Craig Beattie and midfielder Tom Butler will miss the clash at Prenton Park as they are around two weeks away from contention with calf and thigh injuries respectively.
Butler's fellow midfielder Ferrie Bodde (knee) and striker Gorka Pintado (shoulder) are long-term casualties - with the former not expected back until February.
However, winger Nathan Dyer suffered no ill-effects of a leg injury after he played 65 minutes at Carrow Road and will be fine to remain in the starting line-up.
