Steven Davis has been passed fit for the game.
The midfielder suffered a hamstring injury against Aberdeen at the weekend, but is set to take his place after completing training at Murray Park this afternoon.
"He (Davis) was able to train fully at Murray Park and that is a huge plus for manager Walter Smith," a statement on the club's official website said.
James Beattie and John Fleck are both injured, while Nikica Jelavic is ineligible to play in the competition for the Scottish champions.
Gers (from): McGregor, Whittaker, Papac, Weir, Bougherra, Broadfoot, Davis, McCulloch, Edu, Naismith, Miller, Lafferty, Foster, Little, Weiss, Hutton, Alexander, Webster.