Dons skipper Paul Hartley was red carded in Saturday's record 9-0 defeat by Celtic at Parkhead and will serve an automatic one-game ban.
Andy Considine (knee) and Nikola Vujadinovic (hamstring) are still struggling while Peter Pawlett (broken toe) and long-term casualty Fraser Fyvie are out.
Aberdeen (from): Langfield, Diamond, McArdle, Robertson, Folly, Aluko, Young, Jack, Vernon, Magennis, Maguire, Mackie, Ifil, Howard, Velicka, Hansson, Fraser, Shaughnessy.
Inverness are expected to name an unchanged squad.
Midfielder Russell Duncan pulled out of the home defeat by Motherwell with a groin injury and is again doubtful.
Gil Blumenshtein, David Proctor, Chris Innes (all hamstring) and Kenny Gillet (knee) remain on the sidelines.
Inverness (from): Esson, Tokely, Munro, McCann, Cox, Shinnie, Duff, Hayes, Ross, Foran, Rooney, Odhiambo, Sutherland, Golabek, McBain, Tuffey, Morrison, Sanchez.