Bolton boss Owen Coyle will assess his international contingent before deciding on his team to take on the Toffees.
Daniel Sturridge, who withdrew from England Under-21 duty, will be hoping for a second-consecutive start after netting twice in two games since joining on loan from Chelsea.
Jlloyd Samuel (thigh) has returned to training after six months out but is some way short of match fitness while Ricardo Gardner, Joey O'Brien and Sean Davis are also on the sidelines.
Everton have suffered a fresh injury blow with the loss of in-form striker Louis Saha.
The Frenchman, who scored four times in last week's defeat of Blackpool, strained a hamstring this week and is likely to be out for 10-14 days.
The news comes just a day after Everton confirmed midfielder Jack Rodwell could be sidelined for around four weeks with the groin injury sustained on England Under-21 duty.
Defender Phil Jagielka, who recently had a spell out with a thigh injury, is pushing for a start after two substitute appearances.
Bolton (from): Bogdan, Jaaskelainen, Robinson, Cahill, Knight, Wheater, Muamba, Petrov, K Davies, Elmander, Klasnic, Taylor, Ricketts, Alonso, Rodrigo, M Davies, Cohen, Holden, Steinsson, Blake, O'Halloran, Sturridge, Lee.
Everton (from): Howard, Neville, Distin, Heitinga, Jagielka, Baines, Coleman, Cahill, Osman, Fellaini, Arteta, Bilyaletdinov, Beckford, Anichebe, Gueye, Baxter, Duffy, Silva, Mucha.