Norwich midfielder David Fox could return for the clash with Orient.
The former Manchester United trainee has missed the last two matches with a calf injury.
Boss Paul Lambert, who has refused to comment on Burnley's approach for him to take over at Turf Moor, is again without Wes Hoolahan (thigh).
The Irishman has joined Henri Lansbury, Elliott Ward and long-term absentees Stephen Hughes, Steven Smith and Andrew Surman on the casualty list.
Midfielder Owain Tudur Jones is cup-tied having been allowed to play for Yeovil earlier in the competition but new signing Aaron Wilbraham is available as he did not feature for MK Dons.
Norwich have progressed past the third round just three times in the past 15 seasons.
Terrell Forbes returns to the Leyton Orient side for the FA Cup trip to Norwich.
The defender has finally completed a three-match ban for the red card he received in the 8-2 second-round win over Droylsden a month ago.
Forbes will partner Ben Chorley at centre-half with Elliot Omozusi reverting to right-back in place of Andrew Whing, who has returned to Brighton after his loan spell ended.
Omozusi picked up a slight knee injury during the 4-2 win over Colchester on Monday but is expected to be available.
Midfielder Stephen Dawson also hopes to figure despite being struck down with an illness this week.
Striker Ryan Jarvis has returned from a loan spell at Northampton but is cup-tied.