St Johnstone welcome Jody Morris and Jamie Adams back from suspension after the pair sat out the defeat to Celtic at Parkhead last week.
Midfielder Murray Davidson, who missed the trip to Glasgow with an ankle knock, has recovered and is back in the squad.
Inverness will again be without Jonny Hayes, who has an ankle injury and is expected to be out for most of January.
Kenny Gillet and Kevin McCann are both still recovering from knee injuries but David Proctor could return following a hamstring problem.
St Johnstone (from): Enckelman, Maybury, Grainger, Duberry, MacKay, Morris, Adams, Davidson, Anderson, Taylor, May, Craig, Millar, Samuel, MacDonald, Parkin, Smith, Gartland, Caddis, McIntosh.
Inverness (from): Esson, Tokely, Munro, Cox, Proctor, Shinnie, Duff, Ross, Foran, Rooney, Odhiambo, Sutherland, Golabek, Tuffey, Duncan, Sanchez, Innes, Blumenshtein.