Simon Mensing is suspended for Hamilton.
On-loan Cardiff midfielder Aaron Wildig could come in while James Chambers is also available after signing from Shamrock Rovers, although he is short of match-fitness.
Alex Neil (hip) and James Gibson (knee) remain on the sidelines.
Kilmarnock midfielder Alexei Eremenko is suspended, but new signing Willy Aubameyang will come into the squad pending international clearance following his move from AC Milan.
Craig Bryson, James Dayton (both knee) and Alan Combe (groin) remain on the sidelines.
Hamilton (from): Cerny, Elebert, Graham, Canning, Buchanan, McLaughlin, McDonald, Crawford, McAlister, Skelton, Gillespie, Antoine-Curier , Hasselbaink, Imrie, M Paixao, Kirkpatrick, F Paixao, Murdoch, Casalinuovo, Chambers, Wildig.
Kilmarnock (from): Bell, Clancy, Hay, Fowler, Mendes Silva, Wright, Sissoko, Hamill, Taouil, Berntsson, Pascali, Kelly, Eremenko, Rui Miguel, Sammon, Old, Jaakkola, Kennedy, Gross, Aubameyang.