Doncaster boss Sean O'Driscoll is expected to name an unchanged side.
O'Driscoll has had to contend with a series of injuries to various defenders this season but is able to field two centre-halves, Adam Lockwood and Matt Kilgallon, alongside each other in successive matches.
Defender Joe Mills, on loan from Southampton, will be out for another three weeks due to a cracked shin bone and centre-half Wayne Thomas remains sidelined due to a calf strain.
Another defender, George Friend, will start on the bench again following his return from a knee injury alongside Dennis Souza, who gives O'Driscoll an alternative option at the back.
Martin Woods is sidelined again after suffering a recurrence of a groin injury, while fellow midfielders Simon Gillett (knee) skipper Brian Stock (back) will also be missing.
Barnsley central defenders Stephen Foster and Jason Shackell will return to contention for the derby.
Both missed Saturday's 1-1 home draw with Swansea due to respective one-game bans after being sent off in the recent defeat at Hull.
Foster was shown a straight red card but misses just the one game as his dismissal was not for violent conduct.
Midfielder Nathan Doyle and versatile defender Bobby Hassell filled the gap in central defence and manager Mark Robins is expected to make changes.
Jay McEveley and Luke Potter are currently sidelined with knee injuries but Robins has no other new injury or suspension problems.
Striker Danny Haynes made his debut against Swansea and is expected to start again up front alongside Garry O'Connor.