City boss Roberto Mancini has named a strong squad for the first-leg tie in Greece on Tuesday evening.
Leading scorer Carlos Tevez is included even though he has rarely featured in the competition this season, as is Mario Balotelli following a knee problem.
Midfielder Michael Johnson has received a boost after his injury problems by joining the group.
However James Milner is ruled out after being injured in the 2-1 defeat by Manchester United and Nigel de Jong is absent because of an ankle problem.
Man City squad (from): Hart, Given, Taylor, Richards, Zabaleta, Boateng, K Toure, Kompany, Kolarov, Lescott, Wright-Phillips, Vieira, Y Toure, Silva, Barry, Tevez, Dzeko, Balotelli, Jo, M Johnson.