Rory McArdle and Alexander Diamond look set to have recovered from flu for Aberdeen.
Sone Aluko (Achilles) and David McNamee (groin) should be fit but Rob Milsom (foot) is out and Andrew Considine is suspended.
Darren Mackie, Fraser Fyvie and Yoann Folly remain on the long-term absentee list.
Motherwell full-backs Stevie Hammell and Steven Saunders are pushing for a recall for the match.
Saunders has served a one-match suspension and both players are hoping to recover from hamstring problems.
However, manager Stuart McCall has revealed that one or two unnamed players could drop out injured following the 6-0 defeat by Rangers, while Bob McHugh (wrist) remains on the sidelines.
Aberdeen (from): Langfield, McArdle, Smith, McNamee, Diamond, Vujadinovic, Hartley, Jack, Young, Vernon, Maguire, Blackman, Anderson, Aluko, Howard, Pawlett, Paton, Magennis.
Motherwell (from): Randolph, Hateley, Gunning, Hutchinson, Page, Jennings, Forbes, Humphrey, Sutton, Murphy, Pollock, Jeffers, Jones, Casagolda, Lasley, Craigan, Hammell, Saunders.
