Paul Hartley and Andrew Considine are available following suspension as Aberdeen tackle the Accies.
The duo missed last Saturday's 5-0 defeat of Kilmarnock and could struggle to force themselves back into the side.
Peter Pawlett (knee) remains on the sidelines alongside long-term absentees Yoann Folly, Darren Mackie and Fraser Fyvie.
Hamilton have an unchanged squad for the clash.
Dougie Imrie will return from a knock at the weekend while Marco Paixao faces up to four weeks on the sidelines with a knee injury.
Simon Mensing (illness) is still out and club captain Alex Neil (hip) and James Gibson (knee) remain long-term casualties.
Aberdeen (from): Langfield, McNamee, Smith, Considine, Diamond, Vujadinovic, Milsom, Jack, Young, Aluko, Hartley, Maguire, Vernon, Blackman, McArdle, Paton, Magennis, Anderson, Shaughnessy, Howard.
Hamilton (from): Cerny, Buchanan, Canning, McLaughlin, Casalinuovo, Carrington, Routledge, Antoine-Curier, Wildig, F Paixao, McAlister, Murdoch, Skelton, Elebert, Elliott, Chambers, Crawford, Hasselbaink.