Hartlepool first-team coach Mick Wadsworth will assess the fitness of James Brown and Paul Murray.
Striker Brown missed the 2-1 win at Exeter on Saturday with an ankle injury he sustained against Southampton, while experienced midfielder Murray was sidelined with a sore knee.
Both players may come back into contention to face Lee Clark's promotion chasers but left-back Neil Austin, who has missed six games with a calf problem, is once again a doubt.
Wadsworth has no other injury or suspension problems to contend with when his Pools side, who currently occupy 12th place in League One, look to secure back-to-back league wins for only the third time this season.
Huddersfield manager Lee Clark has fitness worries over strikers Jordan Rhodes and Danny Cadamarteri and winger Gary Roberts.
Rhodes returned to the starting line-up against Leyton Orient on Saturday following a recent ankle injury, but was withdrawn at half-time due to illness, while Cadamarteri hurt his back during the warm-up.
Roberts was replaced by Scott Arfield after 29 minutes on Saturday after straining his hamstring.
Town goalkeeper Alex Smithies is hoping to return to the squad following a 10-game lay-off due to a knee injury, but left-back Gary Naysmith will be sidelined for up to a month with a calf injury.
Liam Ridehalgh has stepped in for Naysmith earlier in the season, but is still struggling with glandular fever, so Stephen Jordan, signed on loan from Sheffield United in time to make his debut on Saturday, will continue in the back four.