Fraser Forster and Joe Ledley are suspended for the Bhoys.
Polish number two Lukasz Zaluska will take over from Forster in goal.
Midfielder Beram Kayal returns from suspension and right back Mark Wilson is in contention despite picking up an ankle knock in the 2-0 defeat by Motherwell at Fir Park on Sunday.
Rangers midfielder Vladimir Weiss has been all but ruled out.
The on-loan Manchester City player suffered an ankle injury against St Johnstone on Sunday and is a major doubt, although an X-ray showed no fracture.
Steven Naismith (hamstring) and Jamie Ness (groin) remain out along with long-term absentees Kirk Broadfoot (foot) and Lee McCulloch (knee).
Celtic (from): Zaluska, Wilson, Juarez, Majstorovic, Mulgrew, Izaguirre, Brown, Ki, Kayal, Commons, Stokes, Samaras, Hooper, Murphy, Cervi, Loovens, Rogne, McGinn, McCourt.
Rangers (from): McGregor, Foster, Whittaker, Weir, Papac, Bougherra, Davis, Bartley, Edu, Fleck, Diouf, Healy, Lafferty, Hutton, Jelavic, Alexander.
