Defenders Micah Richards and Jerome Boateng will both be missing as City resume their quest for a Champions League spot.
Richards injured a hamstring on England Under-21 duty a week ago and is out for at least a fortnight, while Boateng faces six weeks on the sidelines once he has knee surgery in the next few days.
Pablo Zabaleta is available after returning from a mercy dash to Argentina to visit his ill father.
Sunderland boss Steve Bruce will be boosted by the return of long-term absentees Fraizer Campbell and Michael Turner to the squad.
Striker Campbell has not made a senior appearance since damaging his knee in the home clash with City on August 29, while central defender Turner has also been sidelined by a knee injury since November 22.
Phil Bardsley (knee) and Sulley Muntari (calf) are expected to be fit, while John Mensah is available after his red card against Liverpool was rescinded. Kieran Richardson (hamstring) is a doubt and Nedum Onuoha is ineligible under the terms of his loan agreement, while David Meyler (knee) remains on the sidelines.
Man City (from): Hart, Taylor, Zabaleta, Kompany, Lescott, Kolarov, Boyata, Wright-Phillips, De Jong, Yaya Toure, Vieira, Barry, Silva, Milner, Adam Johnson, Dzeko, Balotelli, Tevez, Razak.
Sunderland (from): Mignolet, Gordon, Bardsley, Angeleri, Ferdinand, Bramble, Mensah, Turner, Muntari, Cattermole, Riveros, Henderson, Malbranque, Elmohamady, Sessegnon, Zenden, Colback, Gyan, Welbeck, Campbell, Noble, Knott.