City boss Roberto Mancini could be tempted to recall Edin Dzeko to the team.
The Bosnia and Herzegovina striker, a £27million signing from Wolfsburg, scored his first Premier League goal for the club in the victory against Blackburn after stepping off the bench.
Mancini will again be without injured pair Carlos Tevez and Micah Richards (both hamstring) as well as Jerome Boateng (knee).
Scott Parker is set to miss out for West Ham.
The England international is still struggling with an Achilles injury and is almost certain to miss the trip to Eastlands, according to manager Avram Grant.
Parker will be joined on the sidelines by fellow midfielders Mark Noble and Gary O'Neil, who are out with hernia and ankle injuries respectively.
Wayne Bridge is ineligible to feature against his parent club, but the Hammers defence will be boosted by the return of Matthew Upson from a chest infection.
Man City (from): Hart, Taylor, Given, Zabaleta, Kompany, Lescott, Kolarov, Boyata, Wright-Phillips, De Jong, Y Toure, Vieira, Barry, Silva, Milner, A Johnson, Dzeko, Balotelli, Razak, McGivern, Guidetti.
West Ham (from): Green, Jacobsen, Tomkins, Upson, Hitzlsperger, Piquionne, Spector, Ba, Cole, Boffin, Reid, Da Costa, Boa Morte, Obinna, Collison, Keane.