Barnsley striker Marlon Harewood is not expected to win his fitness battle in time for the game.
Harewood, who has scored four goals in 10 appearances for the Tykes since arriving on loan from Blackpool in February, has missed the last two games due to a hamstring injury sustained against Watford.
Teenage striker Danny Rose is also struggling with a knee injury following a training ground collision, but otherwise manager Mark Robins has no other new injury or suspension problems.
Striker Danny Haynes is expected to keep his place alongside Andy Gray after scoring his sixth and seventh goals of the season in last week's derby draw at Sheffield United.
Teenage forwards Jordan Clarke and Reuben Noble-Lazarus are hoping to retain their places on the substitutes' bench as the Tykes look to secure the win needed to overhaul last season's points tally of 54.
Neil Harris is back in the Millwall squad for the trip to Barnsley.
The club's record goalscorer has completed a three-match ban for the red card he was shown just moments after coming on as a substitute against Coventry last month.
Fellow striker Kevin Lisbie is still on the sidelines with an ankle injury so Harris will vie with John Marquis, Josh McQuoid and Hameur Bouazza to partner top scorer Steve Morison in attack.
Long-serving full-back Alan Dunne, who this week signed a new three-year deal, could return to the starting line-up.
Dunne was on the bench for the defeat by Swansea last weekend after suffering a gashed eye against Preston.
Forward Shaun Batt (cruciate) is a long-term absentee.