Aberdeen boss Craig Brown has doubts over Rob Milsom and David McNamee.
Both players picked up knocks in the 1-1 draw at New St Mirren Park on Saturday.
Brown, though, will give both players every chance of declaring themselves fit.
St Mirren boss Danny Lennon has no fresh fitness concerns ahead of the trip.
The Buddies travel to Pittodrie with the same squad which was held to a 1-1 draw with the Dons last Saturday.
David Barron and Garry Brady are still short of fitness following lay-offs.
Aberdeen (from): Langfield, McNamee, McArdle, Diamond, Smith, Aluko, Considine, Vujadinovic, Milsom, Hartley, Vernon, Blackman, Maguire, Magennis, Howard, Young.
St Mirren (from): Gallacher, McAusland, Travner, McGregor, Potter, Murray, Thomson, Goodwin, Dargo, Higdon, McLean, van Zanten, Mair, Mooy, McGowan, Cregg, Wardlaw, Samson.