Zander Diamond is doubtful.
The Dons defender came off during the 2-0 defeat by St Johnstone with a hip injury and is struggling.
Aberdeen boss Craig Brown will consider giving a start to Fraser Fyvie who came off the bench against Saints after recovering from after a cruciate ligament injury.
Jim Goodwin is "very doubtful", according to manager Danny Lennon.
Goodwin limped off with a calf strain 40 minutes into the Paisley side's 1-0 defeat by Inverness on Saturday.
Hugh Murray (knee) is out for the season but Jure Travner is available following suspension.
Aberdeen (from): Langfield, Diamond, Robertson, Smith, Vujadinovic, Young, Milsom, Aluko, Jack, Maguire, Blackman, Fyvie, Magennis, Low, Howard, Grimmer, Anderson, Masson.
St Mirren (from): Gallacher, McAusland, McGregor, Potter, Thomson, Higdon, Travner, Dargo, McLean, Van Zanten, Mair, Mooy, McGowan, Cregg, Barron, McKernon, Wardlaw, Samson.