Marius Zaliukas is set to return to the Hearts team, but the capital club have a host of other concerns.
Eggert Jonsson is available after the club appealed his sending off at Rangers, but Adrian Mrowiec (thigh), Andy Webster (groin), Lee Wallace (ankle), Jason Thomson (hamstring), David Templeton (knock) and Ruben Palazuelos (illness) are all doubtful.
Ismael Bouzid is back from a ban, but Andrew Driver (hernia) Suso Santana (knee), Calum Elliot (knee) and Kevin Kyle (hip) are all out.
Anthony Stokes and Georgios Samaras return from suspension for Celtic.
Defender Emilio Izaguirre has shrugged off a knock picked up against Kilmarnock on Sunday.
Hoops stopper Glenn Loovens has recovered from a strain and is included in the squad.
Hearts (from): Kello, MacDonald, Stevenson, Bouzid, Elliott, Skacel, Glen, C Thomson, J Thomson, Balogh, Webster, Wallace, Templeton, Black, Palazuelos, Robinson, Zaliukas, Mrowiec, Jonsson, Barr, McGowan.
Celtic (from): Forster, Izaguirre, Mulgrew, Loovens, Majstorovic, Wilson, Rogne, Brown, Commons, Ki, Forrest, Maloney, Hooper, McCourt, Stokes, Samaras, Murphy, Zaluska, Juarez, Cha, McGinn.