Adam Clayton is expected to start for the Dons.
Clayton, on loan from Leeds, stepped in for Peter Leven as manager Karl Robinson made nine changes for the final game of the season at Oldham.
The 22-year-old, who Leeds signed for an undisclosed fee from Manchester City last summer, has made six appearances for the Dons since arriving on loan in March. He has also featured for Peterborough this season, on eight occasions during a loan spell from November to March.
Leven has undergone successful surgery on the metatarsal he fractured in training last Thursday.
Robinson has no new injury or suspension problems but is expected to make major changes again for the home leg after resting several players on the last day.
Striker Angelo Balanta is another hoping to retain his place against Posh after starting and scoring in the 2-1 win at Oldham.
Posh manager Darren Ferguson will choose from a virtually fully-fit squad.
Strikers Dave Hibbert and Paul Taylor are Posh's only absentees while midfielders Grant Basey and Charlie Lee are expected to prove their fitness in time.
Hibbert has been sidelined since dislocating his knee in the FA Cup win over Stockport in November and Taylor sustained a foot injury this week during a run-out for the reserves.
Basey has returned to contention after recovering from a knee injury and Lee has been nursing a hamstring strain.
Midfielder Scott Griffiths is also back in contention after returning from his loan spell at Chesterfield and he could be called on if Lee was to suffer a recurrence.