Striker Luis Suarez could play in Liverpool's opening match of the Premier League campaign despite only returning to training on Monday.
The Uruguay international's involvement in winning the Copa America prevented him from featuring in the club's pre-season but manager Kenny Dalglish will consider him for selection.
New signing Jose Enrique has declared himself fit but it remains to be seen whether Dalglish will include the defender in his squad.
Stewart Downing, Charlie Adam, Jordan Henderson and Alexander Doni are all in the squad but captain Steven Gerrard and defender Martin Skrtel are both out and full-back Glen Johnson (hamstring) faces a late fitness test.
Sunderland defender John O'Shea will have to wait to make his Premier League debut for the club after being ruled out.
The Republic of Ireland international, who joined the club from Manchester United during the summer, damaged a hamstring during pre-season and is not yet ready to resume.
Fellow new-boys Keiren Westwood, Wes Brown, Craig Gardner, David Vaughan, Sebastian Larsson, Connor Wickham and Ji Dong-won will all hope to have forced their way into manager Steve Bruce's plans, although Craig Gordon, David Meyler and Fraizer Campbell (all knee) remain on the sidelines.
Liverpool (from): Reina, Johnson, Kelly, Carragher, Agger, Kyrgiakos, Flanagan, Aurelio, Robinson, Lucas, Adam, Spearing, Henderson, Shelvey, Downing, Cole, Meireles, Rodriguez, Kuyt, Suarez, Carroll, Ngog, Doni.
Sunderland (from): Mignolet, Westwood, Bardsley, Brown, Richardson, Turner, Bramble, Ferdinand, Laing, Cattermole, Gardner, Vaughan, Colback, Elmohamady, Gyan, Sessegnon, Wickham, Ji, Cook.