Leeds' new loan signing Andy Keogh is expected to go straight into the starting line-up.
The 25-year-old Republic of Ireland international, signed initially on loan until January, is a likely starter as manager Simon Grayson is still without strikers Luciano Becchio, Billy Paynter and Davide Somma, while winger Max Gradel is suspended.
Becchio (hamstring) and long-term absentee Somma (knee) have yet to play this season and Paynter missed out on Saturday with a thigh strain.
Leeds will also be without suspended skipper Jonny Howson. The midfielder and Gradel were both sent off during Saturday's home defeat to Middlesbrough for two yellow card offences and will sit out respective one-game bans.
Grayson could turn to Ramon Nunez and Lloyd Sam, who both stepped off the substitutes' bench against Middlesbrough, while young defenders Tom Lees, 20, and Zac Thompson, 18, will be hoping to feature again after making their debuts at the weekend.
Hull manager Nigel Pearson will pick from a virtually full-strength squad.
Defender Liam Rosenior (knee), striker Dele Adebola (back) and Aaron Mclean (calf) all returned to action as the Tigers secured their first win of the season at Ipswich.
Rosenior started at Portman Road and is expected to retain his place, while Adebola and Mclean were both late substitutes' and may have to settle for a place on the bench again.
Assistant manager Craig Shakespeare said: "There's a few aches and pains and niggles, but they all reported in [on Sunday].
"They'll train again and there are a couple who might just do a bit less, but we'll wait and see how they are on Tuesday morning."
Defender Paul McShane (calf) and winger Cameron Stewart (knee ligaments) are still unavailable.