Reading are sweating on the fitness of attacking duo Noel Hunt and Hal Robson-Kanu.
Hunt missed last weekend's home defeat to Watford with a back problem and is fighting to be fit for the meeting with Donny, while Robson-Kanu has missed training during the week with a knee injury and is doubtful.
Simon Church bagged two goals for the club's reserve side in midweek and may well feature in manager Brian McDermott's starting line-up, as Reading look to put an end to a dismal run of four consecutive Championship losses.
Adam Le Fondre failed to score on his debut for the first time in his professional career last week and will be hoping to make up for that against the Hornets.
Marcus Williams, meanwhile, has been sent out on loan to Sheffield United.
Doncaster boss Sean O'Driscoll could call upon fit-again duo Shelton Martis and Brian Stock.
Defender Martis and midfielder Stock have been hit by injury in the opening weeks of the campaign but came through 90 minutes of a practice match against Grimsby in midweek.
Yet the Yorkshire outfit remain beset by injuries, with Chris Brown, James Chambers, Martin Woods, Adam Lockwood, Billy Sharp and Ryan Mason all remaining sidelined.
Rovers have yet to win a league game, while Reading have lost their last five after clinching their only victory of the season at Leicester on August 13.
O'Driscoll said: "Obviously confidence on both sides has not been sky high but it's important that we go into the game believing we can play well rather than just hoping that will be the case."