Celtic defender Charlie Mulgrew is suspended for the match while Neil Lennon has revealed stopper Kelvin Wilson could be out for six weeks with an Achilles injury.
Wilson picked up the injury in the 2-0 Scottish Communities Cup third-round win over Ross County in midweek and was due to have a scan on Friday.
Scott Brown (ankle) and Kris Commons (groin) remain on the sidelines but Georgios Samaras (ribs), Mark Wilson (knee) and Paddy McCourt (calf) are back in contention.
Inverness pair Gavin Morrison (ribs) and Richie Foran (shoulder and foot) are touch and go for the clash.
Josh Meekings and Lee Cox are back in training after injury but are unlikely to play.
Chris Hogg, Owain Tudur Jones (both knee), Jonny Hayes and Aaron Doran (both shoulder) are definitely out.
Celtic (from): Forster, Matthews, Majstorovic, Mark Wilson, Wanyama, El Kaddouri, Stokes, Bangura, Ledley, Kayal, Forrest, Hooper, George, Zaluska, Rogne, McCourt, Samaras, Loovens.
Caley (from): Esson, Tokely, Golobart, Ross, Sutherland, Foran, Tade, Piermayr, G Shinnie, A Shinnie, Morrison, Gillet, Chippendale, Davis, McKay, Tansey, Proctor, Tuffey.