On-loan Tottenham midfielder Jermaine Jenas is in contention to make his Aston Villa debut after recovering from a thigh problem.
Record signing Darren Bent has shaken off a groin injury while fellow striker Emile Heskey is also in the frame after a recent hamstring setback.
Villa boss Alex McLeish will give a late fitness test to defender James Collins who suffered an ankle knock against QPR last weekend. Carlos Cuellar, Chris Herd and Eric Lichaj remain sidelined.
Wigan defender Emmerson Boyce is close to a recall having recovered from the hamstring problem which has kept him out of the last two league matches.
His return would be welcome as Steve Gohouri is suspended having been sent off against Tottenham last week.
Fellow defender Antolin Alcaraz (thigh) and striker Hugo Rodallega (knee) are unavailable.
Villa (from): Given, Hutton, Collins, Dunne, Warnock, Jenas, Petrov, Delph, N'Zogbia, Ireland, Bannan, Agbonlahor, Bent, Heskey, Albrighton, Weimann, Given, Delfouneso, Beye, Lowry, Gardner, Clark.
Wigan (from): Al Habsi, Caldwell, Figueroa, Boyce, Lopez, Watson, Diame, Moses, Gomez, Di Santo, Jones, Stam, Van Aanholt, McArthur, McCarthy, Thomas, Sammon, Maloney, Crusat, McManaman, Kirkland.