Exeter welcome back Daniel Nardiello and Jake Taylor.
The pair missed the Grecians' 2-0 defeat to Bury last weekend, Nardiello with a slight knock and Taylor because of Wales Under-21 commitments, but the duo are ready to return.
Defender Richard Duffy is a doubt with an ankle injury, but otherwise Tisdale has the luxury of a fully-fit squad.
Striker John O'Flynn and midfielder Liam Sercombe both started in the loss to Bury after long lay-offs through injury and could keep their places, while centre-back Troy Archibald-Henville is available again after serving a one-match ban.
Defender Scot Bennett is also fighting for a starting berth, having impressed on his full debut for the club last week.
Huddersfield defender Jamie McCombe is back in contention following suspension.
McCombe has completed a three-game ban following his dismissal in the recent draw with Leyton Orient, but manager Lee Clark is expected to stick with club skipper Peter Clarke and Antony Kay in central defence.
Clark has a full-strength squad to choose from barring goalkeeper Alex Smithies as the Terriers look to extend their club-record unbeaten league run to 37 matches.
Smithies, yet to feature this season, will be sidelined until the new year following surgery to resolve a knee problem.
Midfielder Oscar Gobern is back in the reckoning after recovering from a dead-leg and striker Jordan Rhodes is pushing for a recall to the starting line-up after scoring five goals in two games for Scotland Under-21s.