Steve Cotterill will take charge of Forest for the first time when Boro head to the City Ground.
Cotterill, who led Notts County to the League Two title just under 18 months ago, was confirmed as Steve McClaren's successor on Friday after a compensation package was agreed with Portsmouth and he watched from the stands as Forest lost 1-0 to Coventry the following day.
Forest picked up no fresh injury problems at the Ricoh Arena but will remain without a host of players.
Full-back Joel Lynch is still struggling with a thigh complaint and joins long-term casualties Chris Cohen, Dexter Blackstock, Garath McCleary (all knee), Paul Anderson (hamstring) and former Middlesbrough captain George Boateng (ankle) on the sidelines.
Goalkeeper Carl Ikeme will be missing from Middlesbrough's squad for their trip to Nottingham Forest.
Ikeme, on loan from Wolves, missed the 1-1 draw with Millwall on Saturday after injuring his hand in training and has not recovered in time.
Jason Steele played in place of Ikeme as Boro conceded their first goal in over 300 minutes of football against the Lions and he looks set to fill in once more.
Defender Seb Hines is back in training after being out for nearly two months with a knee problem, but he is still doubtful.
Jonathan Franks is also back in training after undergoing surgery on a dislocated shoulder but he will not be risked against Forest.