Kenny Miller is likely to return for Cardiff.
The striker looks set to recover from a groin problem that saw him miss Scotland's Euro 2012 qualifiers as well as Cardiff's last two matches.
However, fellow frontman Rudy Gestede is out having been substituted with a hamstring injury in the 4-3 defeat to Peterborough on Tuesday.
Manager Malky Mackay will also be looking to resolve problems in defence having leaked six goals in the last two matches.
Centre-back Ben Turner, who has returned from a lengthy spell on the sidelines following a knee injury, played both matches and may be rested.
Cardiff are looking to rediscover their early-season form having only won once in their last six league matches.
Barnsley manager Keith Hill must decide whether to retain striker Craig Davies in his starting line-up.
Davies made his first start since August in the midweek win over Burnley after recovering from a groin injury but Hill admitted the summer signing from Chesterfield is not fully match fit.
Davies was replaced by Ricardo Vaz Te midway through the second half on Tuesday night and Hill must decide who to play alongside Andy Gray.
Defenders Bobby Hassell (groin) and Jay McEveley (unspecified) remain doubtful after missing out against Burnley while winger Matty Done and striker Danny Haynes are not yet ready to return following their respective hamstring injuries.
Midfielders David Perkins (hamstring), Reuben Noble-Lazarus (ankle) and Goran Lovre (knee) all remain sidelined as the Tykes chase their third win in four league matches.