Guy Moussi returns from suspension for Forest.
Moussi missed the 1-0 defeat to Hull at the City Ground on Saturday as he served a one-match ban following his red card in the victory at Blackpool the previous weekend.
The French midfielder is likely to go straight back into the starting XI as Steve Cotterill looks for a response from his players after a first loss since his appointment as manager.
"No disrespect to any of the other lads in midfield but we missed Guy Moussi's energy in there," Cotterill said. "That is a big factor in our game. We missed that against Hull. Both Jonathan Greening and Lewis McGugan did well but we definitely missed the energy that Moussi brings."
The Reds will check on the fitness of Greg Cunningham after the on-loan defender was forced off with tight calves and hamstrings late on against Hull. Striker Ishmael Miller also has a groin issue.
Reading manager Brian McDermott may draft Jay Tabb into his squad.
Midfielder Tabb, who suffered a horrible head injury in the win at Burnley on October 15, missed the Championship clashes with Derby and Southampton towards the end of October and was not included in the matchday 16 which drew 0-0 at Crystal Palace on Saturday.
However, Tabb is available for selection if required at the City Ground.
McDermott has no new injury concerns for the meeting with Forest as Reading look to extend their eight-match unbeaten streak in the league.
Winger Jimmy Kebe has shown no adverse reaction since making his return from a month on the sidelines two weeks ago and may start.