Sunderland boss Steve Bruce will be without midfielder Sebastian Larsson through suspension.
The Sweden international will sit out the game after reaching five bookings for the campaign, while striker Connor Wickham is facing weeks on the sidelines with his knee injury.
Defender Titus Bramble, who was expected to play for the reserves in midweek after being fined for bringing the club into disrepute, also has a knee problem and is unavailable, as are keepers Simon Mignolet (fractured nose and eye socket) and Craig Gordon (knee).
Fulham will be without Stephen Kelly on Wearside after the defender suffered a groin injury on Republic of Ireland duty last week. He joins Aaron Hughes (thigh) and Zdenek Grygera (cruciate) on the sidelines.
Midfielder Steve Sidwell is recovering from a minor hernia operation and will be handed a late fitness test.
Sunderland (from): Westwood, Carson, Brown, Bardsley, Richardson, Turner, Laing, Cattermole, Gardner, Vaughan, Larsson, Colback, Elmohamady, Meyler, Sessegnon, Bendtner, Ji, McClean, Cook, Egan, R. Noble.
Fulham (from): Schwarzer, Etheridge, Riise, Hangeland, Baird, Dembele, Briggs, Sidwell, Kasami, Murphy, Gecov, Duff, Etuhu, Dempsey, Johnson, Zamora, Ruiz.