Sheffield Wednesday's new loan signings Sanchez Watt, Miguel Llera and James Tavernier will all be included in the squad.
Arsenal striker Watt, Blackpool centre-half Llera and Newcastle right-back Tavernier joined the Owls this week and manager Gary Megson has several selection dilemmas as he now has six players on loan at Hillsborough and only five can be named in the 16-man squad.
The Owls will be without striker Gary Madine, who broke a toe in last week's win at Tranmere, so Ryan Lowe could return to the starting line-up alongside Chris O'Grady.
Skipper Rob Jones is suspended after receiving his fifth booking of the season at Tranmere and Megson could be tempted to hand Llera his debut alongside another loanee, Danny Batth (Wolves), at the heart of defence.
Versatile defender Lewis Buxton remains sidelined with a hamstring injury as the Owls look to close the gap on league leaders Charlton and second-placed Huddersfield, who play each other on Monday, by extending their unbeaten league run to four matches.
Tony Craig and Lee Cook will be added to the Leyton Orient squad.
Defender Craig has joined on loan from Millwall and winger Cook has arrived from QPR.
Craig is set to slot straight into the starting line-up at left-back in the wake of Charlie Daniels' move to Bournemouth on Thursday.
Cook, whose career has been blighted by injuries, will probably start on the bench until he builds up his match fitness.
Boss Russell Slade moved for the former Watford and Fulham wideman after midfielder Dean Cox was ruled out for a month with a knee injury.
Utility man Leon McSweeney returns to the squad after missing last week's goalless draw against Stevenage through suspension.