Huddersfield's new manager Simon Grayson will be without skipper Peter Clarke for his first game in charge.
Central defender Clarke is recovering from a double hernia operation so Sean Morrison, on loan from Reading, is expected to continue alongside Jamie McCombe at the heart of defence.
Grayson, installed as Lee Clark's successor on Monday, has no new injury or suspension problems, but will also be without Tommy Miller, who is still struggling with a stomach injury.
Fellow midfielder Oscar Gobern should be in contention to retain his place in the starting line-up despite being forced off in the defeat to Sheffield United with a bang to the thigh.
Winger Gary Roberts returned to the starting line-up quicker than expected after recovering from a double hernia operation for the clash with the Blades and should be available again.
Huddersfield are chasing their first League One win in four games as they bid to keep their automatic promotion hopes alive.
Steve Tully is set to return to the Exeter squad.
The defender sustained a hand injury in a 2-1 defeat at Notts County on Valentine's Day, subsequently missing the Grecians' dramatic 3-2 victory over Bury.
But if Tully passes a late check before travelling to the Galpharm Stadium then manager Paul Tisdale will have a fully-fit and suspension-free squad at his disposal.
Artur Krysiak has made the goalkeeping position his own this season, making 32 appearances and keeping nine clean sheets, and his form will be key to reviving the club's fortunes on the road.
With five defeats from their last seven away trips, Tisdale will need Krysiak to keep League One and Terriers' top-scorer Jordan Rhodes at bay.