Bournemouth will be without influential midfielder Marc Pugh for the clash with League One's table-toppers.
Pugh rolled his ankle in training last week, straining a ligament and ruling him out of action for around three weeks.
The Cherries are still without Stephen Purches, whose double leg-break will keep him sidelined for the foreseeable future, while Charlie Sheringham is also out for the season with a foot injury.
Defender Steve Cook has sustained ligament damage and is unlikely to be risked against the Addicks, while Mark Molesley will also be absent because of his own ankle problem.
Captain Adam Barrett is progressing well in his recuperation from a hamstring knock but remains at least a fortnight away from a return to full training, with goalkeeper Shwan Jalal (back) requiring another month before he can be considered for selection.
Leaders Charlton could be unchanged.
Boss Chris Powell has named the same line-up for the last two matches, a 2-0 win over Stevenage and Tuesday night's thumping 4-0 victory at Chesterfield.
Bradley Wright-Phillips grabbed a first career hat-trick against the Spireites and is set to be partnered by Yann Kermorgant again.
Fellow forward Danny Haynes is fit after a recent hamstring problem but will probably have to settle for a place among the substitutes.
Midfielder Bradley Pritchard and winger Scott Wagstaff will hope to make the bench after missing out completely in midweek.
The Addicks have no injury worries and currently lie a healthy 10 points clear of second-placed Sheffield United.