Doncaster will assess a trio of players before the game.
Frederic Piquionne, El-Hadji Diouf and Brian Stock are the three players whose fitness will come under scrutiny as Rovers look to end a run of nine games without a win.
On-loan West Ham striker Piquionne missed the 2-1 home defeat to Burnley with a calf injury but could come back into the frame, while Diouf also sat out the Clarets clash with a leg injury sustained in the heavy loss at Leicester.
Brian Stock replaced Diouf at the King Power stadium but lasted just 22 minutes against Burnley before he too was withdrawn with a knock.
Habib Beye (ankle) is doubtful, while midfielder Martin Woods (knee) and forward Habib Bamogo (hamstring) remain sidelined.
Portsmouth defender Ricardo Rocha has been passed fit for the clash.
The Portuguese centre-half will be available after shaking off the calf injury he suffered during the 1-0 home defeat by Millwall on Tuesday night.
Tal Ben Haim remains on the sidelines with a calf injury and fellow defender Aaron Mokoena has an ankle problem.
Veteran striker Kanu has returned to training following a back injury but is not expected to be involved.
Pompey are currently nine points from safety with four matches remaining.
Rovers, bottom of the table and two points behind, will be relegated unless they win while even a victory would not save them if Bristol City beat Birmingham.