Sheffield United midfielder Lee Williamson is rated "50/50".
Williamson is struggling with a chest muscle injury sustained in Tuesday's win at Rochdale, so Ryan Flynn, who replaced him at half-time at Spotland, could make the starting line-up.
Manager Danny Wilson is boosted by the return to contention of strikers Will Hoskins and James Beattie, who both returned to full training this week after overcoming a virus and a dead leg respectively.
Wilson has no other new injury or suspension problems and is unlikely to make any further changes as his side chase a sixth straight win in pursuit of automatic promotion.
The Blades, in second, are two points ahead of Sheffield Wednesday and six adrift of leaders Charlton with four games remaining.
Leyton Orient will be without Jimmy Smith.
The midfielder this week had an operation on the fractured cheekbone he suffered against Notts County on Good Friday.
He will miss the clash with the promotion-chasing Blades, but Orient hope he could return before the end of the season wearing a protective mask.
Defender Terrell Forbes will be checked over after missing Monday's defeat by Exeter with a groin problem, while utility man Leon McSweeney (calf) and winger Jamal Campbell-Ryce (ankle) are also still struggling with knocks.
Jamie Jones starts in goal with Paul Rachubka on the bench after extending his loan from Leeds until the end of the season.
Fellow keeper Lee Butcher (knee) and defender Scott Cuthbert (hamstring) will not figure again this term.