Darel Russell returns to the Charlton squad.
The on-loan midfielder has missed the last four matches, including the promotion party at Carlisle last weekend, through suspension after he was sent off at Huddersfield last month.
Russell will be hoping for a run-out as he cannot play against his parent club Preston next weekend, while fellow midfielder Danny Hollands completes a three-match ban for his red card at Oldham.
However, manager Chris Powell could name the same line-up for the third straight game as they attempt to wrap up the League One title.
The Addicks will be crowned champions with two games to spare if they secure three points and second-placed Sheffield United fail to beat MK Dons.
Wycombe face a defensive crisis ahead of the trip.
The Addicks, who sealed a return to the Championship with a 1-0 win at Carlisle last weekend, have turned down Wanderers' request to allow defender Gary Doherty to play.
Doherty is on loan at Wycombe from Charlton and boss Gary Waddock had hoped the Addicks would overlook the matter now that their promotion was confirmed.
It leaves Waddock short of options in central defence, with Dave Winfield and Anthony Stewart both major doubts for the game on Saturday. Winfield limped off against Oldham last weekend after suffering a recurrence of a thigh problem, while Stewart missed that game with a knee injury.
Leon Johnson replaced Winfield and Waddock may also have to recall on-loan Sunderland defender Louis Laing, who has not featured for almost a month. However, Danny Foster (shoulder) is closing in on a return after five weeks out and he may be called upon.
Chris Hackett missed the 2-2 home draw with Oldham because of a groin injury but the on-loan winger could come back into the reckoning.