Charlton manager Chris Powell is set to rotate his squad for the title party.
Powell made eight changes to his side for the 2-2 draw at Preston last week having already wrapped up the League One crown.
On-loan Preston midfielder Darel Russell is in line to return to the squad after being ineligible to play at Deepdale.
Russell, Leon Cort, Lee Cook and Dany N'Guessan are available for the final time before their loan spells come to an end.
Goalkeeper Ben Hamer, defenders Rhoys Wiggins and Michael Morrison, skipper Johnnie Jackson, fellow midfielder Dale Stephens and strike duo Bradley Wright-Phillips and Yann Kermorgant will all be hoping for recalls.
The Addicks will be presented with the League One trophy after the game.
Hartlepool skipper Sam Collins is hoping to return from injury.
Pools manager Neale Cooper could wait until the last minute before finalising his line-up as central defender Collins aims to prove his fitness following a calf injury.
Teenager Jack Baldwin has stepped in for the absent Collins in the last two matches and will resume alongside Peter Hartley should his captain fail to make it.
Teenager Darren Holden is hoping to retain his place in the side after making only his second start for the club in last week's win over Leyton Orient, but striker James Brown will miss out again with the groin problem that has kept him sidelined since the end of March.
Forwards Colin Nish and Colin Larkin (both knee) and veteran Nolberto Solano (ill) are unavailable.