MK Dons leading goalscorer Dean Bowditch, fellow striker Charlie MacDonald and midfielder Alan Smith are expected to return.
The trio started on the substitutes' bench in last week's win at Rochdale as manager Karl Robinson made wholesale changes.
But Robinson is likely to field his full-strength starting XI in a bid to secure the win that would guarantee a fourth-place finish and home advantage in the return leg of their play-off semi-final with Huddersfield.
Stephen Gleeson is expected to revert back to his more accustomed role alongside Darren Potter in midfield, with 16-year-old Brendan Galloway, handed his first start at Rochdale, making way.
Midfielder Daniel Powell is hoping to return to the side following his one-game ban.
Robinson has no new injury or suspension problems as the Dons look to register a fifth win in their last six matches.
Walsall will be without influential midfielder Florent Cuvelier.
The loanee has returned to parent club Stoke upon the completion of his maximum 93-day stay, signing off in style as he netted the crucial equaliser in last weekend's 1-1 draw with Huddersfield which assured the Saddlers' League One safety.
Midfielder Adam Chambers comes back into contention having trained all week after a calf injury, as does striker George Bowerman, who shrugged off a foot problem to join in with his team-mates.
Defender Manny Smith is also available having served a one-match suspension last Saturday, leaving manager Dean Smith with a fully-fit squad to select from.