Burnley boss Eddie Howe will be without striker Martin Paterson and winger Keith Treacy.
Paterson would have missed the game against the Brewers due to his Northern Ireland call-up for Wednesday's European Championship qualifier against the Faroe Islands.
However, he succumbed to injury in Saturday's 2-2 draw against Watford after complaining of a niggle.
Paterson is set for a spell on the sidelines, so Charlie Austin, who replaced the Ulsterman at half-time against the Hornets, should land a starting role.
Winger Treacy, who scored a point-saving equaliser against the Hornets, will also miss out as he is in the Republic of Ireland squad to face Croatia in Dublin.
Burton will be without Tom Parkes when they travel to Burnley.
The on-loan Leicester defender was sent off for two bookable offences as Albion began their League Two campaign with a 2-2 draw at last season's play-off finalists Torquay on Saturday.
Parkes will serve a one-match suspension but boss Paul Peschisolido is confident he has enough central defensive cover at his disposal.
"We've got a good set of lads at the club," said the Canadian. "We've got Tony James and Ryan Austin, and Darren Moore is coming back to fitness, so we'll be alright."
Midfielder Jimmy Phillips and striker Greg Pearson will hope for starts after having to settle for substitute roles at the weekend.
