Saints will check on Lee Barnard, who missed Saturday's 3-1 win over Leeds after suffering an ankle injury in pre-season but he is close to a return.
Winger Alex Chamberlain (ankle) and defender Radhi Jaidi (knee) also sat out at the weekend and will not be risked against the League Two Gulls.
Boss Nigel Adkins is likely to make changes so Belgian winger Steve De Ridder, a substitute on Saturday, could be handed his full debut.
Lee Holmes, Dan Seabourne, Danny Butterfield, Morgan Schneiderlin and Richard Chaplow may also be drafted into the starting line-up and Bartosz Bialkowski could get a run-out in goal in place of Kelvin Davis.
Torquay are without Billy Kee with the Northern Irishman being called up for Under-21 duty.
The striker was substituted in their season-opener against Burton with the man replacing him, Taiwo Atieno, likely to make his first competitive start for the Gulls.
Atieno impressed in pre-season, scoring in matches against Tiverton Town and Bristol City, which convinced manager Martin Ling to offer him a one-year-deal.
Twenty-year-old Daniel Leadbitter is in contention to make his debut after recovering from a hamstring complaint that prevented his from making the squad against Burton.
Leadbitter signed a two-year contract following a summer move from Newcastle, and is looking to earn his first start in the Torquay defence.