Marlon King is set to make his long-awaited debut for Birmingham against the Lions.
The striker, a free-transfer signing this summer following the best part of a season at Coventry, has been sidelined since pre-with a knee injury.
Fellow forward Nikola Zigic (groin) is also close to making his return but this weekend could come too soon for him to be involved.
Defender Pablo Ibanez and midfielder Wade Elliott arrived on transfer deadline day and could make their bows as could on-loan midfielder Guirane N'Daw, who has now received international clearance.
Morgaro Gomis is also likely to be available having had the two-week international break to get over his knock but fellow midfielder Jordon Mutch continues to be ruled out long-term with a broken ankle.
Cameron Jerome and Scott Dann completed deadline-day moves to Stoke and Blackburn respectively.
Liam Feeney and Jay Simpson will be added to the Millwall squad for the trip to City.
Winger Feeney was a deadline-day signing from Bournemouth and striker Simpson is back at The Den for a second loan spell.
Forward Dany N'Guessan, who made his loan deal a permanent move from Leicester before the transfer window closed, needs a fitness test on a hamstring injury as does midfielder Liam Trotter.
French midfielder Therry Racon is still sidelined with ankle ligament damage and striker Shaun Batt's recovery from a cruciate injury was disrupted by a calf strain.
Winger Chris Hackett could be on the bench after a back spasm kept him out of the goalless draw with Barnsley last time out.