Shane Long is poised to make his debut for West Brom, but Peter Odemwingie is struggling to overcome the ankle injury suffered in the pre-season friendly at Bristol City a fortnight ago.
Right back Steven Reid (calf) and Youssouf Mulumbu (abdominal strain) are available after injury but summer signing, defender Gareth McAuley, is ruled out through illness.
Patrice Evra is a major doubt for United.
The full-back was forced out of last week's Community Shield win over Manchester City with a knee injury and was not fit enough to play in France's midweek friendly with Chile.
United manager Sir Alex Ferguson confirmed Evra is still struggling, so either Fabio or Jonny Evans will likely step in. Darren Fletcher (virus) and Antonio Valencia are pencilled in for reserve-team appearances on Monday, while Javier Hernandez (concussion) is sidelined for another fortnight.
West Brom (from): Foster, Reid, Tamas, Olsson, Shorey, Mulumbu, Scharner, Brunt, Morrison, Thomas, Long, Odemwingie, Cox, Fulop, Jones, Cech, Tchoyi, Ibanez, Dorrans, Jara, Fortune.
Manchester United (from): De Gea, Lindegaard, Rafael, Smalling, Ferdinand, Vidic, Jones, Evra, Evans, Fabio, Nani, Park, Cleverley, Anderson, Carrick, Giggs, Young, Rooney, Berbatov, Welbeck, Diouf, Owen, Macheda.